William married Luda Elizabeth Springston on 20 Jul 1854 in Jackson Co., VA. Luda (daughter of Abraham Springston and Eva J Effie Goff) was born on 11 Apr 1838 in Gilmer, West Virginia, United States; died on 7 Apr 1912 in Roane County, West Virginia, USA. [Group Sheet] [Family Chart]

1. Dewese Thomas Greathouse and died.
2. John Nelson Greathouse was born in 1855 in West Virginia; died on 5 Aug 1926.
3. Mary Josephine Greathouse was born in 1857 in West Virginia; and died.
4. Abraham Greathouse was born in Apr 1860 in West Virginia, USA; died on 5 Aug 1926.
5. Elizabeth Jane Greathouse was born on 7 Dec 1860 in Virginia; died on 24 Sep 1942 in Spencer, Roane, West Virginia, USA.
6. Margaret Ann Greathouse was born in Dec 1861 in West Virginia; died on 10 Jul 1939; was buried in Spencer, Roane County, West Virginia, United States of America.
7. George Washington Greathouse was born on 16 Dec 1865 in West Virginia; died on 14 Dec 1933 in Wood County, West Virginia, USA.
8. Rachel Rebecca Greathouse was born on 18 Sep 1867 in West Virginia; died on 24 Oct 1943 in Elizabeth, Wirt, West Virginia.
9. Marcellus Greathouse was born on 10 Sep 1869 in West Virginia; died on 30 Apr 1937.
10. Susan Laverna Greathouse was born on 23 Jun 1871 in West Virginia; died on 21 Apr 1896.
11. James William Greathouse was born on 10 Sep 1875 in Spencer, Roane, West Virginia, USA; died on 28 Jun 1937 in Parkersburg, Wood, West Virginia, USA.
12. Calvin Rildow Greathouse was born on 13 Jul 1878 in Spencer, Roane, West Virginia, USA; died on 1 Nov 1957 in Jackson County, West Virginia, USA.
13. Benjamin Franklin Greathouse was born on 24 Jun 1882 in West Virginia; and died.